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Dehydration can worsen gastrointestinal side effects, impair detoxification pathways that glycine supports, and reduce exercise performance that drives muscle preservation

Scenario A- GLP-1s become a standard treatment, like statins for cholesterol

These include semaglutide (Wegovy, Ozempic and Rybelsus), tirzepatide (Mounjaro), and liraglutide, which is sold under several brand names

In the SURMOUNT-1 trial, participants without diabetes lost an average of 15-20% of their body weight over 72 weeks at the 10 mg and 15 mg doses, though results may vary in different populations

The outgoing medication decays while the incoming medication accumulates