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Ratios of classical monocytes (CD14-/CD16-), which are more responsible for phagocytosis and initiation/priming of the immune system [254], are higher in patients with ALS and pre-symptomatic SOD1 carriers as compared with healthy controls, but function at a decreased efficacy and invade the CNS, though the difference between the roles of monocytes in the CNS versus systemic circulation are still unknown [255]

1875-A HEPATITIS C VIRUS SUSTAINED VIROLOGIC RESPONSE (SVR) RATES ARE DISSIMILAR FOR PATIENTS WHO RECEIVED A SINGLE 84-DOSE FILL OF SOFOSBUVIR / VELPATASVIR COMPARED TO PATIENTS WHO RECEIVED A 28-DOSE PRESCRIPTION WITH TWO REFILLS Frederic McCall III 1 , Gia Landry 2 , Lisa Chang 1 , Jessica Fridge 1 , Billy Robinson 3 and Elizabeth N