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The resulting inflammation exacerbates tissue damage and contributes to adverse remodeling of the heart, which can lead to heart failure if not properly managed [93]

Zhang, F

Tauopathy: A group of neurodegenerative diseases that arise concomitant with abnormal tau protein deposition in brain cells

Two naturally occurring compounds, shikonin and allicin (Figure 2), are produced by plant roots, presumptively to combat bacteria in the rhizosphere, an indication that nature has already identified TrxR as an antimicrobial target site

The mechanism of action of various phytoconstituents in garlic as it passes through the gastrointestinal tract is given in Figure 6