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doi: 10.1900/RDS.2011.8.418

Linagliptin lowered plasma glucose levels significantly at 30, 60, 90 and 120-minute during OGTT in high GLP-1 group ( Figures 2A, B )

Taken together, these findings demonstrate that the 10 mg/kg morphine model recapitulates the known effects of opioids in humans, inducing constipation through inhibition of both intestinal transit and motility