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It has been shown using various atherosclerosis animal models that GLP-1RA therapy is associated with a reduction in atherosclerotic plaques, prevention of aorta intima-media thickening, improvement in vascular endothelial function, reduction of the necrotic zone and an increase of the fibrous component in the plaque and plaque stabilisation

Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes

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The growing prevalence of metabolic disease, CKD, and ASCVD have prompted investigation into the role of GLP-1R agonists in mitigating cardiovascular and metabolic risks, particularly within the framework of Cardiovascular-Kidney-Metabolic (CKM) Syndrome, irrespective of diabetic status

This is the ingredient most responsible for the I feel better on these shots reports, and the mechanism is not mysterious: in a patient who is genuinely B12-deficient, repletion resolves fatigue