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Weight loss trajectory was still accelerating Phase 1 (oral): 10.4-13.1% weight loss at 12 weeks depending on dosing regimen vs 1.2% placebo Phase 2 (T2D): SC amycretin showed up to 14.5% weight loss and HbA1c reductions up to 1.8% at 36 weeks

Professional Guidance Follow established, peer-reviewed protocols when available

By subcutaneous injection, often timed at night to align with your natural GH rhythm

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The ggplot2 and pheatmap R software packages were conducted to visualize the DEGs by drawing volcano plots and heatmaps, respectively