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HepaRG cells (8000 cells/25 L/well) or PHHs (Hu8163, 17,500 cells/25 L/well) were seeded in collagen I-coated 384-well white flat-bottom plates (Corning, catalog: 354665)

Seventy percent of study volunteers showed collagen increases compared to untreated controls a response rate significantly higher than that achieved by either comparator compound, both of which are considered first-line clinical options for photoaged skin

Still, the GHK-Cu peptide is not an anti-aging miracle or one-size-fits-all solution

A previous paper (Remien et al., Heptology 56(2012), 727-734) had developed a mathematical model of liver enzymes in the plasma and cell necrosis in the liver in order to predict which patients require liver transplants

Extended exposure above 8C accelerates degradation