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Hypermethylation of GSTP1, CD44, and Ecadherin genes in prostate cancer among US Blacks and Whites

A key innovation was integrating GLP-1R agonism into a GIP peptide scaffold, achieving an agent capable of activating both receptors

Typical daily range: 150600 mcg once daily 150 mcg/day to start, titrating gradually to 600 mcg/day over 8 weeks

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Our analysis of individual outcomes revealed substantial reductions in all-cause mortality, MAKE, and MALO with combination therapy, yielding several significant clinical implications