In the food-effect trial, AUC 024h,semaglutide,day10 (primary endpoint), C max,semaglutide,day10 , AUC 024h,SNAC,day10 and C max,SNAC,day10 were log-transformed and compared between fed (only SNAC endpoints), fasting and reference groups in linear normal models with group and sex as fixed factors
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** Based on the treatment regimen estimand: treatment effect regardless of whether patients stayed on treatment or took other glucose-lowering therapies
It also ensures the supply of oxygen to the cells of the body and increases the metabolism
Hypoglycemia can happen suddenly, and symptoms may differ in each individual and change over time in the same individual