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At baseline, patients reported moderate-to-severe 24-h average pain (numerical rating score

In the body, about 95% of the total choline pool is converted to phosphatidylcholine an essential component of the phospholipid bilayer and the predominant phospholipid in most mammalian cells

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Disturbance of insulin signaling in diabetic patients might lead to the abnormal expression of Syn, damage to mitochondrial function, increase in mitochondrial oxidative stress, and down-regulation of the PI3K/AKT pathway, which in turn could promote the occurrence and development of PD (62)