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Interestingly, the oocyte maturation was blocked at a very specific development stage (metaphase I arrest) where a sensor for DNA damage (Spindle Assembly Check point/Dna Damage Response) assesses the DNA integrity and blocks the oocyte maturation through the activation of a protein (ATM kinase)

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Laboratory tests that check HbA1c, lipid profiles, and how the pancreas works can find possible problems

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