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Coenzyme Q10 modulates the immunity by enhancing mononuclear macrophage, NK cell activity, and regulating gut microbiota

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However, clinical trials in chronic heart failure with reduced ejection fraction (HFrEF), such as the LIVE trial, have yielded mixed or modestly negative results

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There is even speculation of whether longevity could be impacted, since obesity and diabetes reduction improve life expectancy some analysts have asked if GLP-1 drugs might earn their discoverers a Nobel Prize given the broad impact ( [152] )