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Although kidney disease events have thus far been secondary outcomes in clinical trials, an ongoing phase III trial in patients with diabetic kidney disease will test the effect of a GLP1R agonist on a primary kidney disease outcome
Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, et al
Most users inject into their abdomen or thigh once per week
However, in infants born to people with type 2 diabetes who took a second-line noninsulin antidiabetic medication including GLP-1 receptor agonists the study did not find a greater major congenital malformation risk compared to infants exposed to insulin
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