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However, a landmark July 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) by Shankar, Davis, Bonilla, et al., revealed a fascinating and complex paradox regarding redox homeostasis in these conditions

Enhanced Insulin Sensitivity Research suggests AOD-9604 may improve insulin sensitivity in fat cells , supporting better glucose utilization and metabolic health in treated areas

This pH-adaptive stability spans both physiological skin acidity (pH 46) and the alkaline extremes (pH 79) typical for chronic wounds, confirming the ability of D-CuP to maintain structural integrity under pathological conditions

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Patch testing, following recommended usage guidelines, and consulting your dermatologist are key to maximising the benefits while minimising the risks