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No human safety data : The complete absence of human clinical trials means the safety profile, side effects, optimal dosing, and pharmacokinetics in humans are entirely unknown Animal-to-human translation is uncertain : Metabolic differences between mice and humans mean that the magnitude of effects (e.g., weight loss, grip strength improvement) may not translate

It is a synthetic peptide - a short chain of 15 amino acids - that was originally derived from a protein found in human gastric juice

Researchers examine it for its relationship to amylin receptor signaling, appetite-related biological pathways, glucose-adjacent metabolic regulation, and energy-balance systems

We have also examined in details the topographic distribution of the various phosphoproteins in the c-MET/HGF pathway in SCLC tumour tissue