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Supplementary Information The online version contains supplementary material available at 10.1007/s11096-023-01694-7

Week 3, right arm

Melanotan-2: Broad Activation MT-2 activates all five melanocortin receptor subtypes : MC1R Melanin production (tanning) MC3R Energy homeostasis, sexual arousal MC4R Appetite regulation, sexual function, erectile response MC5R Sebaceous gland function This non-selective binding is why MT-2 produces tanning AND sexual effects AND appetite suppression AND nausea it's hitting every melanocortin pathway at once

1, 3-butadiene

During this test the following compounds were analyzed: NAC, MESNA, MPG, Capropril, and LA