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Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers

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To explore whether epigenetic regulation contributes to the basal repression of MAPKAPK2, in silico CpG island prediction using MethPrimer identified dense CpG motifs within the MAPKAPK2 promoter region (Figure 1D), implicating potential DNA methylationmediated regulation

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