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The fluorescence microscopy using JC-1 probe showed the disappearance of mitochondrial membrane potential in all treated cells (Fig

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Keywords: obesity, therapeutics, nicotinamide N-methyltransferase, inhibitors, weight loss Graphical abstract 1

GLUT9 initially identified as the glucose transporter serves acritical role in urate reabsorption (Ebert et al., 2017)

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