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Comparing Clinical Evidence: GLP-1 Receptor Agonists vs Antioxidant Therapy Randomized controlled trials of semaglutide, including SUSTAIN and STEP studies, consistently show significant weight loss, improved blood sugar control, and reduced cardiovascular risk markers

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These results suggest that Sema treatment can improve impaired mitochondrial respiration and mitochondrial structural disturbances in TAC-induced pathological myocardial remodeling

Available online: [DOI] [PMC free article] [PubMed] [Google Scholar] 29.Schloss J.M., Colosimo M., Airey C., Masci P., Linnane A.W., Vitetta L