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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 35% by weight of the povidone

doi: 10.1038/nature23890 28 DuMChenZJ

The pharma is currently seeking further clarification for the rejection, with an eye toward quickly addressing the FDAs comments, according to its news release

It is important to distinguish between plasma levels and intracellular red blood cell levels, as most other glutathione products have only shown increases in plasma levels