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However, significant distinctions were evident between active smokers and former smokers (p = 0.020 in the unmatched group and 0.060 in the matched group), as well as between non-smokers and former smokers (p = 0.010 in the unmatched group and 0.001 in the matched group)

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CSC increases the expression of inflammatory cytokines (IL-1, IL-6, TNF-), VEGF, and HIF-1 in HMEECs To determine the effect of CSC on inducing inflammation in HMEECs, we evaluated the effect of CSC at concentrations of 20, 40, and 80 g/mL on the upregulation of IL-1, IL-6, and TNF- mRNA expression