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25 / An α-mannose-6-phosphate (Man6P) ligand equipped with a terminal carboxylic acid through a short butyl spacer
α-D-Man-Et-NH2
the sialylation of therapeutic proteins can affect their serum half-life
6-tetra-O-acetyl-α-D-mannopyranosyl)-L-threonine
Fmoc-Asn(beta-D-GlcNAc(Ac)3)-OH
GA431000: Fmoc-Thr(Gal(Ac)4-β-D)-OH Pack Size:100 mg 25 / An α-mannose-6-phosphate (Man6P)C33H37NO14 671. 65 An Fmoc protected L threonine building block carrying a D galactose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert
