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According to Tobacco Free CA, Research has shown that even very small amounts of nicotine can be harmful or even lethal to animals. Very similar to Cigarette butts, Puff Bars pollute the environment through runoff and leakage of their chemicals into environments, primarily through waterways (Truth Initiative, Tobacco and the Environment)

Nicotine users often become alcoholics or binge eaters when they quit for a lengthy period

Also, laws are tightening: disposables may be banned, flavorings more strictly defined, online sales more regulated

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A list of countries, and the rates charged, is available here