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mimicking the inner N-glycan substructure released by endo-β-mannosidase activity
This compound presents an A2 biantennary N-glycan capped with α2-6-linked sialic acid (disialo) on an Asn core
73 / / Vitamin E-d3 (R
This process is catalyzed by a group of enzymes known as sialyltransferases
This compound enables the construction of hepatocyte-targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR)
AG142010: α-GalNAc-Butyl-Carboxy Methyl Ester Pack Size:50 mg mimicking the inner N-glycan substructureC14H25NO8 335. 35 An D N acetylgalactosamine (GalNAc) ligand equipped with a methyl ester protected carboxylic acid through a short butyl spacer. The methyl ester serves as a stable, protected form of the carboxylic acid that can be hydrolyzed under mild basic conditions (e. g., LiOH, NaOH) to unmask the free acid for downstream activation to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and subsequent coupling to amine functionalized platforms or
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