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After activating GLP-1R, Semaglutide acetate promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis

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Product information for GLP-1 receptor agonists includes guidance on recognising pancreatitis symptoms (persistent severe abdominal pain, often radiating to the back, with or without vomiting) and advises discontinuation if acute pancreatitis is suspected