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Always prioritize professional guidance when considering dietary changes or supplementation related to MTHFR mutations

Furthermore, TMAO increased aortic plaque area and altered bile acid composition in male ApoE (-/-) mice, accelerating aortic lesions by modifying bile acid profiles, activating FXR and small heterodimer partner, and inhibiting bile acid synthesis (136)

Yet, a deficiency exists in as many as 43% of older adults (4)

The MSSG therefore recommends that healthcare professionals prescribe these medicines in line with their authorised use(s) only, taking into account guidance issued by national authorities or applicable national therapeutic guidelines

The study surveyed around 14,000 members of the weight-loss program WeightWatchers (WW) who were taking medications like Wegovy, Mounjaro, or older drugs such as metformin