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We reasoned that the HR domain of ACTL6A exerts an impact on ferroptosis
Notably, this GIP-related enhancement of energy expenditure is not dependent on classical adipose tissue browning, as we did not observe upregulation of browning/beiging signature genes ( Ucp1 , Prdm16 , Dio2 , Cidea ) in eWAT
Several studies indicate that GLP-1 affects bone homeostasis with a proposed gutbone axis [62]
While the FDA does not explicitly approve these medications for weight loss, semaglutide has received approval for weight management under the brand name Wegovy
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