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Trials were also excluded if pain was not a central symptom of the condition

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However, not all users of tobacco products may develop the urge to try addictive substances

The UK Government recently committed to investing in mass media campaigns and stop smoking services to deter uptake of smoking and help existing smokers to quit

With the latest round of tobacco excise hikes set to bring prices up to $40 a packet by 2020, desperate smokers have turned to illegal means of getting their nicotine fix