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The following high oxytocin receptor brain regions were evaluated: CG1 (cingulate cortex region 1), perirhinal cortex (PRCx), anterior olfactory nucleus (AoN), nucleus accumbens (NAC), lateral septal nucleus (LSV), bed nucleus of the stria terminalis (BNST), ventral reuniens nucleus (Vre), paraventricular nucleus (PVN), hippocampal CA1 and CA2/3 regions, and the central amygdaloid nucleus (Amc)

The most significant published evidence to date comes from a phase 2 randomised controlled trial published in the New England Journal of Medicine in 2023, which evaluated retatrutide across multiple doses in adults with obesity

The guidelines include prioritising Wegovy to individuals with prediabetes and type 2 diabetes

[DOI] [PubMed] [Google Scholar] 46.Yang G., Lei Y., Inoue A., Piao L., Hu L., Jiang H., Sasaki T., Wu H., Xu W., Yu C., et al

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