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The process of freezing and then thawing a liquid peptide solution can cause ice crystals to form that physically damage the peptides structure, leading to significant degradation

This series of phase 3, randomised, double-blind, placebo-controlled clinical trials involved more than 25,000 individuals with overweight or obesity and has extensively demonstrated the efficacy of once-weekly subcutaneous semaglutide 2.4 mg in promoting weight loss [13, 38,39,40,41,42,43,44,45,46]

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