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Cost remains a barrier with a persons income being a major factor in determining compliance with GLP1-RAs (Rodriguez et al., 2025)

A proper diet and adequate sunlight may help maintain vitamin levels in the long term, but supplementation is often necessary

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The most commonly reported adverse effects are gastrointestinal , including: Nausea Bloating and flatulence Diarrhoea (particularly at higher doses above 12 g daily) Abdominal discomfort These effects are typically mild and often resolve with continued use or dose reduction