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5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) the enzyme that methylates nicotinamide (NAM) to 1-methylnicotinamide (1-MNA) using S-adenosyl-methionine (SAM) as the methyl donor

This is called the initial loading phase

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In wellness and metabolic-support settings, 5-Amino-1MQ is commonly used to help support individuals experiencing: Excess body fat Difficulty with weight management Reduced metabolic efficiency Age-related changes in metabolism Fat accumulation resistant to lifestyle changes 5-Amino-1MQ is not intended to diagnose, treat, cure, or prevent disease and should be used under professional supervision