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All the remaining patients (n=45) were evaluated for luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2), progesterone (P), androstenedione (A), testosterone (T), insulin, C peptide, total cholesterol, HDL, LDL, glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) concentrations

The direct comparison upon using the same concentration of ruthenium of the molecular agent Ru(II)-OH and NP4 showed a significantly higher tumor accumulation of the nanoparticle formulation NP4 (Supplementary Fig