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Berberine's hydrophilic quaternary ammonium structure significantly impedes passive skin penetration required for transdermal delivery
Adv Healthcare Mater, 2022, 11: 2101926 Acknowledgements This work was supported by the National Natural Science Foundation of China (62175262), the Science and Technology Innovation Program of Hunan Province (2022RC1201), the Fundamental Research Fund for the Central South Universities (2020CX021), the Key R & D plan of Hunan Province (2022SK2101), and the Scientific Research Launch Project for new employees of the Second Xiangya Hospital of Central South University
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The interaction of nutrients with the small and large intestine generates feedback that slows gastric emptying, induces satiation, and reduces postprandial glycemic excursions
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