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GLP-1 vs GLP-2 comes down to one precursor protein and two very different jobs: GLP-1 (glucagon-like peptide-1) controls appetite, insulin, and satiety, which is why it became the basis for Ozempic, Wegovy, and Zepbound, while GLP-2 (glucagon-like peptide-2) grows and repairs the lining of the intestine, which is why its only approved drug, teduglutide, treats short bowel syndrome rather than obesity

Effects of six months treatment with liraglutide among patients with psoriasis and obesity, beyond metabolic control

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(9) This suggests that Pinealon might be relevant in mitigation of the long-term cardiac remodeling associated with post-myocardial infarction dysfunction