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In summary, CTGF causes synovial fibrosis by activating fibroblast and their transition into myofibroblast, stimulates the production of pro-inflammatory cytokines and thus promotes synovitis and catabolic, destructive processes in the articular cartilage of OA patients

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others argue that osteoporosis takes years to develop and cant be blamed on a single year of treatment

Novo Nordisk, the pharmaceutical company that makes both Wegovy and Ozempic, says it does not sell Wegovy or semaglutide for the purposes of compounding with other products