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This ensures it works well and is safe for the patient

Emma F, Hoff WV, Hohenfellner K, Topaloglu R, Greco M, Ariceta G, Bettini C, Bockenhauer D, Veys K, Pape L, Hulton S, Collin S, Ozaltin F, Servais A, Deschenes G, Novo R, Bertholet-Thomas A, Oh J, Cornelissen E, Janssen M, Haffner D, Rava L, Antignac C, Devuyst O, Niaudet P, Levtchenko E (2021) An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis

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Lysyl oxidase-like 2 (LOXL2)-mediated cross-linking of tropoelastin

Further, one chaperone upregulated during the UPR is Protein Disulfide Isomerase (PDI), which is an essential redox-sensitive activator of PERK (Kranz et al., 2017)