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The Journal of clinical psychiatry, 2017

Ultimately, the burden of responsibility should be placed on the retailer, rather than the underage purchaser, and PUP laws, as well as any associated criminal penalties, should be replaced with a civil penalty structure

Vintage Shagreen cigarette case, Made in England, Art Deco circa 1930-39

Although e-cigarette aerosols contain fewer toxic chemicals, e-liquid constituents and device features are more diverse and customizable than cigarettes (Figure 3)

Excessive consumption leads to severe complications, such as psychosis, panic attacks, or dangerously high heart rates, especially when combined with other substances (polysubstance use)