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While the VPA-induced ASD model effectively recapitulates neurodevelopmental and gastrointestinal phenotypes associated with prenatal environmental insults [43], we acknowledge it does not fully represent the genetic heterogeneity of human ASD

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Moving toward a systems-level understanding, empowered by interactomics, CRISPR technologies, AI-driven modeling and precision biomarker science, will profoundly transform how we interpret disease biology and develop therapeutics

When applicable, this article included references to seminal articles in the field, even if they were published after the search period

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