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Peth B, Vncsa S, Vradi A, Agcs G, Mtrai , Zszkaliczky-Iker F, et al

Temporary dose reduction during illness or significant life stress is reasonable, with resumption of escalation once circumstances normalize

65 In another well-designed study, 187 mg of a similar peppermint oil product taken three times daily before meals for eight weeks led to a significant improvement over placebo with regard to abdominal discomfort, abdominal pain, and quality of life, but not in terms of diarrhea, constipation, or bloating