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The altered cytosolic redox environment promotes the synthesis of new GSH, whereby the overall glutathione pool signicantly increases

Mitochondrial dysfunction in type 2 diabetes mellitus: an organ-based analysis

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718 A prospective study evaluating the relationship between plasma ferroptosis biomarkers and prognosis during the hyperacute phase of endovascular thrombectomy (EVT) in patients with acute ischemic stroke found that stroke patients had higher levels of 4-HNE before and after EVT and lower levels of soluble transferrin receptor (sTFR) 24 h after EVT compared with controls

Therefore, in cancer metabolism and cancer cell survival, cysteine plays an essential role in redox regulation of cellular status and protein function