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The inducers are: (1) ACSL4, as a major regulator in the pathophysiology of ferroptosis, which stimulates it by increasing the content of long PUFAs and omega-6 PUFAs in the cell membrane ( Research Progress Into Ferroptosis in Ophthalmology The clinical application of ferroptosis is currently mainly being studied in terms of nervous system diseases, tumors, and ischemia/reperfusion injury

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These indirect mechanisms can affect energy levels during treatment

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Therefore, understanding the molecular mechanisms and signaling pathways of ferroptosis may provide new diagnostic and therapeutic approaches for regulating liver cell survival and death in AIH [248]