PLoS ONE 15(6):e0234297 Chaulin AM, Grigorieva JV, Suvorova GN, Duplyakov DV (2021) Experimental modeling of hypothyroidism: principles, methods, several advanced research directions in cardiology
Lower GSH levels increase the risk of tissue damage from oxidative stress and affect functions like making molecules and neurotransmitters, detoxifying and balancing hormones, and producing energy
They are clinical landmines
Second, the -glutamylcysteine product is coupled to glycine via GSH synthetase (GSS) to produce GSH or reduced GSH ( via GSH-dependent peroxidase-catalyzed reactions ( T2DM is a chronic metabolic disease characterized by hyperglycemia, prolonged elevated levels of glucose, and insulin resistance
dosing adjustments may be needed Delayed gastric emptying: may affect the absorption of oral meds and peri-anesthesia aspiration riskpatients should let their doctor know they are taking Mounjaro (or any GLP-1) prior to anesthesia-requiring procedures Diabetic retinopathy: can acutely worsen with rapid glycemic improvement in those with T2Dconsider baseline/ongoing eye care While these risks are low, your provider will weigh them against the benefits before prescribing
