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doi: 10.3390/antiox11030599 [DOI] [PMC free article] [PubMed] [Google Scholar] 17.Huang S, Rompolas P

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An increasing body of preclinical and clinical evidence suggests that mitochondrial dysfunction, characterized by bioenergetic failure, heightened oxidative stress, dysregulated calcium handling, and impaired mitophagy, contributes to the etiopathogenesis of both CVDs and cognitive impairment