In the pathogenesis of AD, A plays a key driver in triggering numerous pathophysiological processes, including oxidative stress, synaptic plasticity impairment, and apoptosis, which are key contributors to cognitive decline [6]
Estrogen normally helps keep blood vessels flexible, so when levels fall, vessels can become stiffer, making them more prone to damage
We note that MR-Egger regression has lower statistical power compared to other methods (e.g., IVW) due to its reliance on the Instrument Strength Independent of Direct Effect (InSIDE) assumption and its sensitivity to weak instruments
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You might feel perfectly healthy until a stressful event suddenly increases your bodys energy demands and triggers a dangerous cardiac event [11]