Whereas general obesity and central adiposity, in particular, are the primary factors responsible for the development of insulin resistance, postprandial increases in insulin secretion causes a further expansion of the adipose tissue mass, which further worsens insulin resistance
However, these over-the-counter products are not FDA-approved medications and contain no actual GLP-1 receptor agonists
An editor for the Wall Street Journal, Bradley Olson, recently detailed his experience after he lost 40 pounds while taking Mounjaro, then stopped taking the medication
Even if medications reduce appetite naturally, the body still benefits from a diet that supports lean mass
It established two cohorts: 244,063 patients in the GLP-1 RA treatment group (Victoza, Saxenda, Ozempic, Wegovy) and 11,439,560 patients in the non-GLP-1 RA group