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By binding to copper at the active site of tyrosinase and interfering with melanin synthesis intermediates, glutathione reduces overall melanin formation. As a powerful antioxidant, glutathione also reduces free radicalinduced oxidative stress, which is one of the triggers for increased tyrosinase activity and melanin production

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Additionally, research professionals have demonstrated that DSIP administration can influence the release of pituitary hormones, such as adrenocorticotropic hormone (ACTH) and luteinizing hormone, both of which play a critical role in the stress response and regulating metabolism