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Consistent with our in vitro results, zinc supplementation significantly reduced the proportion of cells while increasing the proportions of cells, bi-hormonal INS + GCG + cells, and tdTomato + GCG + cells (Fig

It is designed to mimic the natural GLP-1 hormone, which regulates insulin secretion and appetite

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Rapid improvement in blood glucose levels, while generally beneficial, may temporarily worsen diabetic retinopathy in susceptible individuals

The political dynamics -- balancing pharmaceutical industry interests against patient access and cost concerns -- make the legislative outcome difficult to predict