Unlike other forms of regulated cell death, cuproptosis is characterized by the direct binding of reduced copper (Cu + ) to lipoylated proteins of the tricarboxylic acid (TCA) cycle, most notably dihydrolipoamide S-acetyltransferase (DLAT), together with destabilization of iron-sulfur (Fe-S) cluster proteins such as succinate dehydrogenase complex ironsulfur subunit B (SDHB) 164
For non-standard anchor doses or per-anchor draw volumes, use the KLOW Calculator or GLOW Calculator
This study was supported by Agricultural Product Quality and Safety Risk Assessment Project (GJFP20230402)
instead, it indirectly affects NAD+ by inhibiting an enzyme called NNMT (nicotinamide N-methyltransferase)
: 25 : 20 : , L- (15%), ( ), , ( ), ( , -, ), (E471)