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Topical delivery, while still nascent for neurological applications, shows promise for peripheral nerve and dermatological models

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Receptor selectivity studies have confirmed Dermorphins substantial preference for mu over delta and kappa opioid receptors with selectivity ratios documenting many-fold preference for MOR in competitive binding assays and establishing the pharmacological basis for its use as a selective MOR research tool in studies requiring clean receptor subtype discrimination

73 JangH.AhnD.ChangS.KimH.LeeB.KimS.et al (2023)